Nereus Pharmaceuticals











    Media Contact:

    Pam Lord
    Porter Novelli Life Sciences
    619-849-6003
    plord@pnlifesciences.com



Nereus Pharmaceuticals Appoints Frank V. Atlee to Board of Directors

San Diego, California - October 24, 2000 - Nereus Pharmaceuticals, Inc., an emerging leader in drug discovery and development, announced today the appointment of Frank V. AtLee to its board of directors, effective immediately. Mr. AtLee is chairman of the board of directors of Monsanto Company, a U.S. based multinational corporation that provides integrated technology-based agricultural solutions for growers and downstream customers in agricultural markets.

Previously, Mr. AtLee served as president of American Cyanamid Company and chairman of Cyanamid International. Mr. AtLee was a member of the board of directors of American Cyanamid Company and currently serves as a director of Takeda Italia Farmaceutici S.p.A.

"Having completed its state of the art new pharmaceutical laboratory, Nereus is poised to accelerate its drug discovery efforts from proprietary microbial sources. Simultaneously, Nereus is rapidly advancing its lead oral TNF-àlpha synthesis inhibitor," said Jean Delage, Managing General Partner of Alta Partners. "Mr. AtLee brings to Nereus over 25 years of general management experience at the highest levels, particularly as it relates to drug discovery and pharmaceutical product development. With human clinical trials projected to begin next year for our lead oral TNF-àlpha synthesis inhibitor and with numerous corporate alliances under consideration, we feel fortunate to have Mr. AtLee's vast experience to help guide our company to the next level of achievement," said Nereus' President and CEO, Kobi Sethna.

In addition to Frank AtLee, Nereus board members include Jean Deleage, Managing General Partner, Alta Partners, San Francisco CA, Standish Fleming, President and CEO, Forward Ventures Services Corporation, San Diego CA, and Kobi Sethna.



About Nereus Pharmaceuticals, Inc.
Nereus Pharmaceuticals is an innovative drug discovery and development company pursuing untapped sources of chemical diversity. With unmatched expertise in marine microbiology and structural elucidation, Nereus is using its integrated platform technologies to identify novel biologically active compounds. The company believes that its marine microbes will be the next great source of drug discovery for the pharmaceutical industry. Nereus aims to develop and optimize drug candidates to treat cancer, infectious diseases, and inflammation. The company's lead compounds, a small molecule, oral TNF-àlpha and IL-1 synthesis inhibitor and a novel anti-cancer agent, are progressing through preclinical development. Nereus is privately held and based in San Diego, California. For more information, visit www.nereuspharm.com.